InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BMP15

Summary

InnateDB Protein

IDBP-689311.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BMP15

Protein Name

Bone morphogenetic protein 15

Synonyms

bmp-15;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000056137

InnateDB Gene

IDBG-637314 (BMP15)

Protein Structure

UniProt Annotation

Function

May be involved in follicular development. Seems to be an oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005125	cytokine activity
GO:0008083	growth factor activity

Biological Process

GO:0001541	ovarian follicle development
GO:0060016	granulosa cell development

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001839 Transforming growth factor-beta, C-terminal
IPR002405 Inhibin, alpha subunit
IPR029034 Cystine-knot cytokine

PFAM

PF00019

PRINTS

PR00669

PIRSF

SMART

SM00204

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q6PX77

PhosphoSite

PhosphoSite-

TrEMBL

Q8MII6

UniProt Splice Variant

Entrez Gene

353351

UniGene

Bt.22954

RefSeq

NP_001026922

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AJ489251 AJ534391 AY304484 AY572412 DQ463368 EU712722

GenPept

AAP68831 AAS99651 ABE97096 ACE78269 ACE78270 CAD32989 CAD58882