Version 5.4
Bos taurus Protein: RNF2
Summary
InnateDB Protein IDBP-689377.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNF2
Protein Name E3 ubiquitin-protein ligase RING2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000000025
InnateDB Gene IDBG-637367 (RNF2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 182 interaction(s) predicted by orthology.
Predicted by orthology
Total 182 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
GO:0071535 RING-like zinc finger domain binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0000278 mitotic cell cycle
GO:0001702 gastrulation with mouth forming second
GO:0009948 anterior/posterior axis specification
GO:0016574 histone ubiquitination
GO:0035518 histone H2A monoubiquitination
GO:0036353 histone H2A-K119 monoubiquitination
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0000791 euchromatin
GO:0000792 heterochromatin
GO:0001739 sex chromatin
GO:0005634 nucleus
GO:0016604 nuclear body
GO:0031519 PcG protein complex
GO:0035102 PRC1 complex
GO:0071339 MLL1 complex
Protein Structure and Domains
PDB ID
InterPro IPR001841 Zinc finger, RING-type
IPR018957 Zinc finger, C3HC4 RING-type
PFAM PF13639
PF14634
PF00097
PRINTS
PIRSF
SMART SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5MA78
UniProt Splice Variant
Entrez Gene 540090
UniGene Bt.102990
RefSeq NP_001094673
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY857620 BC148044 DAAA02043606
GenPept AAI48045 AAW22606

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca