InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KIR3DL2

Summary

InnateDB Protein

IDBP-68947.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KIR3DL2

Protein Name

killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2

Synonyms

CD158K; NKAT-4; NKAT4; NKAT4B; p140;

Species

Homo sapiens

Ensembl Protein

ENSP00000325525

InnateDB Gene

IDBG-407589 (KIR3DL2)

Protein Structure

UniProt Annotation

Function

Receptor on natural killer (NK) cells for HLA-A alleles. Inhibits the activity of NK cells thus preventing cell lysis.

Subcellular Localization

Cell membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0006968	cellular defense response
GO:0050776	regulation of immune response

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003599 Immunoglobulin subtype
IPR013151 Immunoglobulin

PFAM

PF00047

PRINTS

PIRSF

SMART

SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P43630

PhosphoSite

PhosphoSite-P43630

TrEMBL

O78200

UniProt Splice Variant

Entrez Gene

3812

UniGene

Hs.654605

RefSeq

NP_006728

HUGO

HGNC:6339

OMIM

604947

CCDS

CCDS12906

HPRD

10384

IMGT

EMBL

AY789067 DQ979371 EU272658 L41270 L76665 L76666 U30272 X93595 X93596 X94373 X94374 Y11358

GenPept

AAA69871 AAB36593 AAB36594 AAB52520 AAX23112 ABL09827 ABZ02164 CAA63791 CAA63792 CAA64150 CAA64151 CAA72192