Version 5.4
Bos taurus Protein: PPP1R3C
Summary
InnateDB Protein IDBP-689526.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R3C
Protein Name Protein phosphatase 1 regulatory subunit 3C
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000019753
InnateDB Gene IDBG-637511 (PPP1R3C)
Protein Structure
UniProt Annotation
Function Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types (By similarity). {ECO:0000250UniProtKB:Q7TMB3}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019903 protein phosphatase binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0005977 glycogen metabolic process
GO:0005978 glycogen biosynthetic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR005036 Putative phosphatase regulatory subunit
IPR017434 Protein phosphatase 1, glycogen targeting subunit, Metazoa
PFAM PF03370
PRINTS
PIRSF PIRSF038207
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0VCR4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 539466
UniGene Bt.13484
RefSeq NP_001069632
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120042 BT030698
GenPept AAI20043 ABS45014

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca