Version 5.4
Bos taurus Protein: MED29
Summary
InnateDB Protein IDBP-689578.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MED29
Protein Name Mediator of RNA polymerase II transcription subunit 29
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000027226
InnateDB Gene IDBG-637561 (MED29)
Protein Structure
UniProt Annotation
Function Component of the mediator complex, a complex that can either repress or activate transcription. Mediator complexes are essential for basal and regulated expression of nearly all RNA polymerase II-dependent genes. They may act as a bridge, conveying regulatory information from enhancers and other control elements to the promoter (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 59 interaction(s) predicted by orthology.
Predicted by orthology
Total 59 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0016592 mediator complex
Protein Structure and Domains
PDB ID
InterPro IPR021018 Mediator complex, subunit Med29, metazoa
PFAM PF11568
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A1A4Q8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 614626
UniGene Bt.44619
RefSeq NP_001073785
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC126813
GenPept AAI26814

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca