Version 5.4
Bos taurus Protein: BT.43451
Summary
InnateDB Protein IDBP-689638.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.43451
Protein Name transcription elongation factor SPT5
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000041740
InnateDB Gene IDBG-637602 (BT.43451)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 55 interaction(s) predicted by orthology.
Predicted by orthology
Total 55 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0019899 enzyme binding
GO:0044822 poly(A) RNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006354 DNA-dependent transcription, elongation
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0016239 positive regulation of macroautophagy
GO:0032784 regulation of DNA-templated transcription, elongation
GO:0032785 negative regulation of DNA-dependent transcription, elongation
GO:0032786 positive regulation of DNA-templated transcription, elongation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0032044 DSIF complex
Protein Structure and Domains
PDB ID
InterPro IPR005100 Transcription elongation factor Spt5, NGN domain
IPR005824 KOW
IPR006645 NusG, N-terminal
IPR008991 Translation protein SH3-like domain
IPR017071 Transcription elongation factor Spt5
PFAM PF03439
PF00467
PF02357
PRINTS
PIRSF PIRSF036945
SMART SM00739
SM00738
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BC98
UniProt Splice Variant
Entrez Gene 519808
UniGene
RefSeq NP_001076908
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02047059 DAAA02047060 DAAA02047061 DAAA02047062
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca