Version 5.4
Bos taurus Protein: SNAP29
Summary
InnateDB Protein IDBP-689682.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNAP29
Protein Name Synaptosomal-associated protein 29
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000027666
InnateDB Gene IDBG-637659 (SNAP29)
Protein Structure
UniProt Annotation
Function SNAREs, Soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Probably involved in multiple membrane trafficking steps (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. Note=Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000046 autophagic vacuole fusion
GO:0006810 transport
GO:0006914 autophagy
GO:0015031 protein transport
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0016020 membrane
GO:0030054 cell junction
GO:0031201 SNARE complex
GO:0043005 neuron projection
GO:0045202 synapse
Protein Structure and Domains
PDB ID
InterPro IPR000727 Target SNARE coiled-coil domain
PFAM PF05739
PRINTS
PIRSF
SMART SM00397
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0II86
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 532261
UniGene
RefSeq NP_001069427
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC122755
GenPept AAI22756

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca