Version 5.4
Bos taurus Protein: PTF1A
Summary
InnateDB Protein IDBP-689712.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTF1A
Protein Name pancreas specific transcription factor, 1a
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000056491
InnateDB Gene IDBG-637689 (PTF1A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
GO:0046983 protein dimerization activity
GO:0070888 E-box binding
Biological Process
GO:0009790 embryo development
GO:0009888 tissue development
GO:0010842 retina layer formation
GO:0021549 cerebellum development
GO:0030154 cell differentiation
GO:0030902 hindbrain development
GO:0031016 pancreas development
GO:0035881 amacrine cell differentiation
GO:0045165 cell fate commitment
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048384 retinoic acid receptor signaling pathway
GO:0048663 neuron fate commitment
GO:0048699 generation of neurons
GO:0060042 retina morphogenesis in camera-type eye
GO:0061074 regulation of neural retina development
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID
InterPro IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
PFAM PF00010
PRINTS
PIRSF
SMART SM00353
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G5E6S8
UniProt Splice Variant
Entrez Gene 781540
UniGene
RefSeq XP_002707767
HUGO HGNC:23734
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02035454
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca