InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: HELLS

Summary

InnateDB Protein

IDBP-689887.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HELLS

Protein Name

helicase, lymphoid-specific

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000007848

InnateDB Gene

IDBG-637847 (HELLS)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.

Predicted by orthology
Total	20 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding

Biological Process

GO:0001655	urogenital system development
GO:0006306	DNA methylation
GO:0006342	chromatin silencing
GO:0006346	methylation-dependent chromatin silencing
GO:0007275	multicellular organismal development
GO:0010216	maintenance of DNA methylation
GO:0031508	centromeric heterochromatin assembly
GO:0043066	negative regulation of apoptotic process
GO:0046651	lymphocyte proliferation
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway

Cellular Component

GO:0000775	chromosome, centromeric region
GO:0005634	nucleus
GO:0005721	centromeric heterochromatin

Protein Structure and Domains

PDB ID

InterPro

IPR000330 SNF2-related
IPR001650 Helicase, C-terminal
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00176
PF00271

PRINTS

PIRSF

SMART

SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite