Version 5.4
| Bos taurus Protein: MAOA | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-689935.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | MAOA | ||||||||
| Protein Name | Amine oxidase | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000021570 | ||||||||
| InnateDB Gene | IDBG-637884 (MAOA) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. | ||||||||
| Subcellular Localization | Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR001613
Flavin amine oxidase IPR002937 Amine oxidase IPR002938 Monooxygenase, FAD-binding IPR003953 FAD binding domain IPR006076 FAD dependent oxidoreductase IPR023753 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain |
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| PFAM |
PF01593
PF01494 PF00890 PF01266 PF07992 |
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| PRINTS |
PR00757
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| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | P21398 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | C5IXL2 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 281293 | ||||||||
| UniGene | Bt.91572 | ||||||||
| RefSeq | NP_851357 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC122682 EF672353 EF679774 EF679776 FJ972191 X15609 | ||||||||
| GenPept | AAI22683 ABV24965 ABV44455 ABV44457 ACR66918 CAA33632 CAA33633 | ||||||||