InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: LPIN1

Summary

InnateDB Protein

IDBP-689982.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LPIN1

Protein Name

lipin 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000040997

InnateDB Gene

IDBG-637844 (LPIN1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001085	RNA polymerase II transcription factor binding
GO:0003713	transcription coactivator activity
GO:0005515	protein binding
GO:0008195	phosphatidate phosphatase activity
GO:0042826	histone deacetylase binding
GO:0042975	peroxisome proliferator activated receptor binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0000266	mitochondrial fission
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006629	lipid metabolic process
GO:0006642	triglyceride mobilization
GO:0009062	fatty acid catabolic process
GO:0016311	dephosphorylation
GO:0019432	triglyceride biosynthetic process
GO:0031065	positive regulation of histone deacetylation
GO:0031529	ruffle organization
GO:0031532	actin cytoskeleton reorganization
GO:0032869	cellular response to insulin stimulus
GO:0045598	regulation of fat cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:2001141	regulation of RNA biosynthetic process

Cellular Component

GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR007651 Lipin, N-terminal
IPR013209 LNS2, Lipin/Ned1/Smp2
IPR017986 WD40-repeat-containing domain
IPR023214 HAD-like domain

PFAM

PF04571
PF08235
PF00702
PF08282
PF13419

PRINTS

PIRSF

SMART

SM00775

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E1BPE8

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

HGNC:13345

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02031896 DAAA02031897

GenPept