InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: XRCC2

Summary

InnateDB Protein

IDBP-690118.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

XRCC2

Protein Name

DNA repair protein XRCC2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000041269

InnateDB Gene

IDBG-638079 (XRCC2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000400	four-way junction DNA binding
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008094	DNA-dependent ATPase activity

Biological Process

GO:0000278	mitotic cell cycle
GO:0000724	double-strand break repair via homologous recombination
GO:0001701	in utero embryonic development
GO:0006200	ATP catabolic process
GO:0006259	DNA metabolic process
GO:0006281	DNA repair
GO:0006974	cellular response to DNA damage stimulus
GO:0010165	response to X-ray
GO:0010332	response to gamma radiation
GO:0042148	strand invasion
GO:0043524	negative regulation of neuron apoptotic process
GO:0050769	positive regulation of neurogenesis
GO:0051297	centrosome organization

Cellular Component

GO:0005657	replication fork
GO:0005813	centrosome
GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex

Protein Structure and Domains

PDB ID

InterPro

IPR013632 DNA recombination and repair protein Rad51, C-terminal
IPR020588 DNA recombination and repair protein RecA-like, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF08423

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-