Version 5.4
| Bos taurus Protein: GNG12 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||
| InnateDB Protein | IDBP-690132.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | GNG12 | ||||||||
| Protein Name | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000009857 | ||||||||
| InnateDB Gene | IDBG-638091 (GNG12) | ||||||||
| Protein Structure |
|
||||||||
| UniProt Annotation | |||||||||
| Function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. | ||||||||
| Subcellular Localization | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Present in all tissues tested. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
|
||||||||
| Gene Ontology | |||||||||
Molecular Function |
|
||||||||
| Biological Process |
|
||||||||
| Cellular Component |
|
||||||||
| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR001770
G-protein, gamma subunit IPR015898 G-protein gamma-like domain |
||||||||
| PFAM |
PF00631
|
||||||||
| PRINTS |
PR00321
|
||||||||
| PIRSF | |||||||||
| SMART |
SM00224
|
||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q28024 | ||||||||
| PhosphoSite | PhosphoSite-Q28024 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 286850 | ||||||||
| UniGene | Bt.77334 | ||||||||
| RefSeq | NP_777210 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC142068 U37561 | ||||||||
| GenPept | AAC48490 AAI42069 | ||||||||