Version 5.4
Bos taurus Protein: TST
Summary
InnateDB Protein IDBP-690162.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TST
Protein Name Thiosulfate sulfurtransferase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000040894
InnateDB Gene IDBG-638123 (TST)
Protein Structure
UniProt Annotation
Function Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA (By similarity). Formation of iron-sulfur complexes and cyanide detoxification. Binds molecular oxygen and sulfur. {ECO:0000250}.
Subcellular Localization Mitochondrion matrix.
Disease Associations
Tissue Specificity Expressed in numerous tissues.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004792 thiosulfate sulfurtransferase activity
GO:0005515 protein binding
GO:0008097 5S rRNA binding
GO:0016740 transferase activity
Biological Process
GO:0008152 metabolic process
GO:0030855 epithelial cell differentiation
GO:0035928 rRNA import into mitochondrion
GO:0051029 rRNA transport
Cellular Component
GO:0005615 extracellular space
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001763 Rhodanese-like domain
PFAM PF00581
PRINTS
PIRSF
SMART SM00450
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P00586
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 783512
UniGene Bt.89197
RefSeq NP_803455
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC112580 BT020995 M58561
GenPept AAA30753 AAI12581 AAX09012

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca