InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: KCNH1

Summary

InnateDB Protein

IDBP-690305.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KCNH1

Protein Name

potassium voltage-gated channel subfamily H member 1

Synonyms

bEAG; EAG;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000011477

InnateDB Gene

IDBG-638247 (KCNH1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000155	phosphorelay sensor kinase activity
GO:0004871	signal transducer activity
GO:0005216	ion channel activity
GO:0005249	voltage-gated potassium channel activity
GO:0005515	protein binding

Biological Process

GO:0000160	phosphorelay signal transduction system
GO:0006355	regulation of transcription, DNA-templated
GO:0006810	transport
GO:0006811	ion transport
GO:0006813	potassium ion transport
GO:0007165	signal transduction
GO:0023014	signal transduction by phosphorylation
GO:0042391	regulation of membrane potential
GO:0055085	transmembrane transport
GO:0071805	potassium ion transmembrane transport

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000014 PAS domain
IPR000595 Cyclic nucleotide-binding domain
IPR000700 PAS-associated, C-terminal
IPR001610 PAC motif
IPR003938 Potassium channel, voltage-dependent, EAG/ELK/ERG
IPR003949 Potassium channel, voltage-dependent, EAG
IPR003967 Potassium channel, voltage-dependent, ERG
IPR005821 Ion transport domain
IPR013767 PAS fold
IPR018490 Cyclic nucleotide-binding-like

PFAM

PF13188
PF13426
PF00027
PF00520
PF00989

PRINTS

PR01463
PR01464
PR01470

PIRSF

SMART

SM00091
SM00100
SM00086

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt