InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TRDMT1

Summary

InnateDB Protein

IDBP-690398.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TRDMT1

Protein Name

tRNA (cytosine-5-)-methyltransferase

Synonyms

DNMT2;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000027378

InnateDB Gene

IDBG-638310 (TRDMT1)

Protein Structure

UniProt Annotation

Function

Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003723	RNA binding
GO:0008168	methyltransferase activity
GO:0008175	tRNA methyltransferase activity
GO:0016740	transferase activity

Biological Process

GO:0006306	DNA methylation
GO:0008033	tRNA processing
GO:0030488	tRNA methylation
GO:0032259	methylation

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001525 C-5 cytosine methyltransferase
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PF00145

PRINTS

PR00105

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q7YS61

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

353353

UniGene

RefSeq

NP_861528

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AY244708 BT021768

GenPept

AAP20550 AAX46615