Bos taurus Protein: FGD4
Summary
InnateDB Protein IDBP-690452.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FGD4
Protein Name FYVE, RhoGEF and PH domain containing 4
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000007175
InnateDB Gene IDBG-638371 (FGD4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0046872 metal ion binding
Biological Process
GO:0030032 lamellipodium assembly
GO:0030035 microspike assembly
GO:0032321 positive regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
GO:0015629 actin cytoskeleton
GO:0030027 lamellipodium
GO:0030175 filopodium
Protein Structure and Domains
PDB ID
InterPro IPR000219 Dbl homology (DH) domain
IPR000306 FYVE zinc finger
IPR001849 Pleckstrin homology domain
IPR011011 Zinc finger, FYVE/PHD-type
IPR017455 Zinc finger, FYVE-related
PFAM PF00621
PF01363
PF00169
PRINTS
PIRSF
SMART SM00325
SM00064
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1B9P1
UniProt Splice Variant
Entrez Gene 505234
UniGene Bt.91301
RefSeq XP_002687755
HUGO HGNC:19125
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02013889 DAAA02013890 DAAA02013891
GenPept