InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CRB2

Summary

InnateDB Protein

IDBP-690725.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CRB2

Protein Name

crumbs homolog 2 (Drosophila)

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000040914

InnateDB Gene

IDBG-638644 (CRB2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0019828	aspartic-type endopeptidase inhibitor activity
GO:0019899	enzyme binding

Biological Process

GO:0001707	mesoderm formation
GO:0001756	somitogenesis
GO:0010718	positive regulation of epithelial to mesenchymal transition
GO:0010951	negative regulation of endopeptidase activity
GO:0014028	notochord formation
GO:0030513	positive regulation of BMP signaling pathway
GO:0045199	maintenance of epithelial cell apical/basal polarity
GO:0072358	cardiovascular system development

Cellular Component

GO:0043234	protein complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000742 Epidermal growth factor-like domain
IPR001791 Laminin G domain
IPR001881 EGF-like calcium-binding domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR013111 EGF-like domain, extracellular

PFAM

PF00008
PF00054
PF02210
PF07645
PF07974

PRINTS

PIRSF

SMART

SM00181
SM00210
SM00282
SM00179

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite