Bos taurus Protein: CLDN18 | |||||||||||
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Summary | |||||||||||
InnateDB Protein | IDBP-690734.2 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | CLDN18 | ||||||||||
Protein Name | Claudin-18 | ||||||||||
Synonyms | |||||||||||
Species | Bos taurus | ||||||||||
Ensembl Protein | ENSBTAP00000019421 | ||||||||||
InnateDB Gene | IDBG-638652 (CLDN18) | ||||||||||
Protein Structure | |||||||||||
UniProt Annotation | |||||||||||
Function | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}. | ||||||||||
Subcellular Localization | Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. | ||||||||||
Disease Associations | |||||||||||
Tissue Specificity | |||||||||||
Comments | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||
PDB ID | |||||||||||
InterPro |
IPR003928
Claudin-18 IPR004031 PMP-22/EMP/MP20/Claudin superfamily IPR006187 Claudin |
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PFAM |
PF00822
PF13903 |
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PRINTS |
PR01448
PR01077 |
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PIRSF | |||||||||||
SMART | |||||||||||
TIGRFAMs | |||||||||||
Post-translational Modifications | |||||||||||
Modification | |||||||||||
Cross-References | |||||||||||
SwissProt | Q0VCN0 | ||||||||||
PhosphoSite | PhosphoSite- | ||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 511460 | ||||||||||
UniGene | Bt.22727 | ||||||||||
RefSeq | NP_001068984 | ||||||||||
HUGO | |||||||||||
OMIM | |||||||||||
CCDS | |||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | BC120090 | ||||||||||
GenPept | AAI20091 | ||||||||||