Version 5.4
Bos taurus Protein: GRIK5
Summary
InnateDB Protein IDBP-690752.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GRIK5
Protein Name glutamate receptor, ionotropic, kainate 5
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000015567
InnateDB Gene IDBG-638647 (GRIK5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0004970 ionotropic glutamate receptor activity
GO:0005215 transporter activity
GO:0005216 ion channel activity
GO:0005234 extracellular-glutamate-gated ion channel activity
GO:0005515 protein binding
GO:0015277 kainate selective glutamate receptor activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane
GO:0034220 ion transmembrane transport
GO:0035235 ionotropic glutamate receptor signaling pathway
GO:0035249 synaptic transmission, glutamatergic
GO:0042391 regulation of membrane potential
GO:0060079 regulation of excitatory postsynaptic membrane potential
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030425 dendrite
GO:0032983 kainate selective glutamate receptor complex
GO:0042734 presynaptic membrane
GO:0045202 synapse
GO:0045211 postsynaptic membrane
Protein Structure and Domains
PDB ID
InterPro IPR001320 Ionotropic glutamate receptor
IPR001508 NMDA receptor
IPR001638 Extracellular solute-binding protein, family 3
IPR001828 Extracellular ligand-binding receptor
IPR019594 Glutamate receptor, L-glutamate/glycine-binding
IPR028082 Periplasmic binding protein-like I
PFAM PF00060
PF00497
PF01094
PF10613
PRINTS PR00177
PIRSF
SMART SM00079
SM00062
SM00918
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BKL6
UniProt Splice Variant
Entrez Gene 537698
UniGene
RefSeq NP_001039889
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02047229 DAAA02047230 DAAA02047231
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca