Version 5.4
Bos taurus Protein: IL4R
Summary
InnateDB Protein IDBP-690880.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL4R
Protein Name interleukin-4 receptor subunit alpha
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000002098
InnateDB Gene IDBG-638778 (IL4R)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004896 cytokine receptor activity
GO:0005515 protein binding
Biological Process
GO:0002532 production of molecular mediator involved in inflammatory response
GO:0019221 cytokine-mediated signaling pathway
GO:0042832 defense response to protozoan
GO:0043032 positive regulation of macrophage activation
GO:0045626 negative regulation of T-helper 1 cell differentiation
GO:0045630 positive regulation of T-helper 2 cell differentiation
GO:0090197 positive regulation of chemokine secretion
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043235 receptor complex
Protein Structure and Domains
PDB ID
InterPro IPR003961 Fibronectin, type III
IPR015319 Interleukin-4 receptor alpha, N-terminal
PFAM PF00041
PF01108
PF09238
PRINTS
PIRSF
SMART SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q148M2
UniProt Splice Variant
Entrez Gene 404154
UniGene Bt.45933
RefSeq NP_001068610
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC118151 DAAA02057867
GenPept AAI18152

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca