Version 5.4
Bos taurus Protein: PSMD5
Summary
InnateDB Protein IDBP-690911.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PSMD5
Protein Name 26S proteasome non-ATPase regulatory subunit 5
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000022548
InnateDB Gene IDBG-638807 (PSMD5)
Protein Structure
UniProt Annotation
Function Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5 (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0044183 protein binding involved in protein folding
Biological Process
GO:0006457 protein folding
Cellular Component
GO:0008540 proteasome regulatory particle, base subcomplex
GO:0022624 proteasome accessory complex
Protein Structure and Domains
PDB ID
InterPro IPR016024 Armadillo-type fold
IPR019538 26S proteasome non-ATPase regulatory subunit 5
PFAM PF10508
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0P5A6
PhosphoSite PhosphoSite-
TrEMBL F1N6Z0
UniProt Splice Variant
Entrez Gene 515021
UniGene Bt.1773
RefSeq NP_001069161
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120300 DAAA02024783 DAAA02024784
GenPept AAI20301

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca