Version 5.4
Bos taurus Protein: RABEP2
Summary
InnateDB Protein IDBP-691041.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RABEP2
Protein Name Rab GTPase-binding effector protein 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000008595
InnateDB Gene IDBG-638931 (RABEP2)
Protein Structure
UniProt Annotation
Function Plays a role in membrane trafficking and in homotypic early endosome fusion. {ECO:0000250}.
Subcellular Localization Cytoplasm. Early endosome {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0008083 growth factor activity
Biological Process
GO:0006810 transport
GO:0006897 endocytosis
GO:0015031 protein transport
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005769 early endosome
Protein Structure and Domains
PDB ID
InterPro IPR003914 Rabaptin
IPR015390 Rabaptin, GTPase-Rab5 binding domain
IPR018514 Rabaptin coiled-coil domain
PFAM PF09311
PF03528
PRINTS PR01432
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A4FUG8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 511736
UniGene Bt.62765
RefSeq NP_001076877
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114873
GenPept AAI14874

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca