Version 5.4
Bos taurus Protein: FAM168B
Summary
InnateDB Protein IDBP-691090.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAM168B
Protein Name Protein FAM168B
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000052234
InnateDB Gene IDBG-638977 (FAM168B)
Protein Structure
UniProt Annotation
Function Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC27 (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, perinuclear region {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell projection, axon {ECO:0000250}. Note=Expressed in neuronal cell bodies and axonal fibers. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030424 axon
GO:0042995 cell projection
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A8E639
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 505853
UniGene Bt.55355
RefSeq NP_001103260
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AAFC03092902 BC153831
GenPept AAI53832

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca