InnateDB Protein
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IDBP-691184.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ST6GALNAC6
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Protein Name
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Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
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Synonyms
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siat7f; st6GalNAc-VI;
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000053714
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InnateDB Gene
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IDBG-639065 (ST6GALNAC6)
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Protein Structure
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Function |
Alpha-2,6-sialyltransferase involved in the synthesis of alpha-series gangliosides. Has activity toward GD1a, GT1b and GM1b. Has no activity toward glycoproteins. Responsible for the biosynthesis of DSGG (disialylgalactosylgloboside) from MSGG (monosialylgalactosylgloboside) in kidney (By similarity). {ECO:0000250}.
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Subcellular Localization |
Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
Accession |
GO Term |
GO:0001665
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alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity
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GO:0008373
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sialyltransferase activity
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GO:0016740
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transferase activity
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GO:0016757
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transferase activity, transferring glycosyl groups
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001675
Glycosyl transferase, family 29
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PFAM |
PF00777
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q08E15
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
407222
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UniGene |
Bt.64800
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RefSeq |
NP_001001151
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AJ620949
BC123467
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GenPept |
AAI23468
CAF06586
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