Version 5.4
Bos taurus Protein: POLR2D
Summary
InnateDB Protein IDBP-691202.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLR2D
Protein Name DNA-directed RNA polymerase II subunit RPB4
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000013496
InnateDB Gene IDBG-639081 (POLR2D)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 37 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003697 single-stranded DNA binding
GO:0003727 single-stranded RNA binding
GO:0003824 catalytic activity
GO:0003899 DNA-directed RNA polymerase activity
GO:0031369 translation initiation factor binding
Biological Process
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0006351 transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0031990 mRNA export from nucleus in response to heat stress
GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex
GO:0044237 cellular metabolic process
GO:0045948 positive regulation of translational initiation
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005634 nucleus
GO:0005665 DNA-directed RNA polymerase II, core complex
Protein Structure and Domains
PDB ID
InterPro IPR005574 RNA polymerase II, Rpb4
IPR006590 RNA polymerase II, Rpb4, core
IPR010997 HRDC-like
PFAM PF03874
PRINTS
PIRSF
SMART SM00657
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q1JQ91
UniProt Splice Variant
Entrez Gene 617422
UniGene Bt.4253
RefSeq NP_001069926
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC116155 DAAA02003881
GenPept AAI16156

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca