InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TRIM8

Summary

InnateDB Protein

IDBP-691365.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TRIM8

Protein Name

tripartite motif containing 8

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000028059

InnateDB Gene

IDBG-639219 (TRIM8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.

Predicted by orthology
Total	40 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity
GO:0046872	metal ion binding

Biological Process

GO:0032897	negative regulation of viral transcription
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087	innate immune response
GO:0046597	negative regulation of viral entry into host cell
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:1902187	negative regulation of viral release from host cell

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0016605	PML body
GO:0043231	intracellular membrane-bounded organelle

Protein Structure and Domains

PDB ID

InterPro

IPR001841 Zinc finger, RING-type
IPR018957 Zinc finger, C3HC4 RING-type

PFAM

PF13639
PF14634
PF00097

PRINTS

PIRSF

SMART

SM00184

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E1BJC6

UniProt Splice Variant

Entrez Gene

782444

UniGene

Bt.9660

RefSeq

NP_001178405

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02059021

GenPept