Version 5.4
Bos taurus Protein: LRP8
Summary
InnateDB Protein IDBP-691367.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LRP8
Protein Name low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000050885
InnateDB Gene IDBG-639215 (LRP8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0030229 very-low-density lipoprotein particle receptor activity
Biological Process
GO:0006897 endocytosis
GO:0006898 receptor-mediated endocytosis
GO:0021766 hippocampus development
GO:0021819 layer formation in cerebral cortex
GO:0045860 positive regulation of protein kinase activity
Cellular Component
GO:0005901 caveola
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043235 receptor complex
Protein Structure and Domains
PDB ID
InterPro IPR000033 LDLR class B repeat
IPR000742 Epidermal growth factor-like domain
IPR001881 EGF-like calcium-binding domain
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
IPR009030 Insulin-like growth factor binding protein, N-terminal
PFAM PF00058
PF00008
PF07645
PF00057
PRINTS PR00261
PIRSF
SMART SM00135
SM00181
SM00179
SM00192
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F6PYA5
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:6700
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02008849 DAAA02008850 DAAA02008851 DAAA02008852
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca