InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TAOK2

Summary

InnateDB Protein

IDBP-691397.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TAOK2

Protein Name

TAO kinase 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000023163

InnateDB Gene

IDBG-639254 (TAOK2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003677	DNA binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0031434	mitogen-activated protein kinase kinase binding

Biological Process

GO:0000186	activation of MAPKK activity
GO:0006468	protein phosphorylation
GO:0006950	response to stress
GO:0006974	cellular response to DNA damage stimulus
GO:0008360	regulation of cell shape
GO:0030036	actin cytoskeleton organization
GO:0031572	G2 DNA damage checkpoint
GO:0032874	positive regulation of stress-activated MAPK cascade
GO:0046330	positive regulation of JNK cascade
GO:0048041	focal adhesion assembly
GO:0051403	stress-activated MAPK cascade

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0043235	receptor complex

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR009057 Homeodomain-like
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt