Version 5.4
Bos taurus Protein: ARHGDIB
Summary
InnateDB Protein IDBP-691408.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARHGDIB
Protein Name Rho GDP-dissociation inhibitor 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000007933
InnateDB Gene IDBG-639268 (ARHGDIB)
Protein Structure
UniProt Annotation
Function Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005094 Rho GDP-dissociation inhibitor activity
GO:0005096 GTPase activator activity
Biological Process
GO:0043547 positive regulation of GTPase activity
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000406 RHO protein GDP dissociation inhibitor
IPR014756 Immunoglobulin E-set
PFAM PF02115
PRINTS PR00492
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9TU03
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 327676
UniGene Bt.4757
RefSeq NP_786991
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF182001 BC102109
GenPept AAF00938 AAI02110

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca