Version 5.4
Bos taurus Protein: SPN
Summary
InnateDB Protein IDBP-691473.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPN
Protein Name leukosialin
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000037201
InnateDB Gene IDBG-639328 (SPN)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001562 response to protozoan
GO:0001808 negative regulation of type IV hypersensitivity
GO:0001934 positive regulation of protein phosphorylation
GO:0007162 negative regulation of cell adhesion
GO:0007166 cell surface receptor signaling pathway
GO:0031295 T cell costimulation
GO:0042102 positive regulation of T cell proliferation
GO:0042130 negative regulation of T cell proliferation
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process
GO:0042742 defense response to bacterium
GO:0045060 negative thymic T cell selection
GO:0050688 regulation of defense response to virus
GO:0050776 regulation of immune response
GO:0050868 negative regulation of T cell activation
GO:0097190 apoptotic signaling pathway
Cellular Component
GO:0001931 uropod
GO:0005604 basement membrane
GO:0005615 extracellular space
GO:0005887 integral component of plasma membrane
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A6QQP5
UniProt Splice Variant
Entrez Gene 614645
UniGene Bt.85659
RefSeq NP_001096572
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149936 DAAA02057901
GenPept AAI49937

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca