Version 5.4
Bos taurus Protein: PGAP3
Summary
InnateDB Protein IDBP-691558.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PGAP3
Protein Name Post-GPI attachment to proteins factor 3
Synonyms PERLD1;
Species Bos taurus
Ensembl Protein ENSBTAP00000034758
InnateDB Gene IDBG-639401 (PGAP3)
Protein Structure
UniProt Annotation
Function Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins. Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Mainly localizes to Golgi apparatus. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0016788 hydrolase activity, acting on ester bonds
Biological Process
GO:0006505 GPI anchor metabolic process
GO:0006506 GPI anchor biosynthetic process
Cellular Component
GO:0000139 Golgi membrane
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031227 intrinsic component of endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID
InterPro IPR007217 Per1-like
PFAM PF04080
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A7YWP2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 513258
UniGene Bt.62404
RefSeq NP_001098833
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC134683
GenPept AAI34684

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca