Version 5.4
Bos taurus Protein: CREBL2
Summary
InnateDB Protein IDBP-691576.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CREBL2
Protein Name cAMP-responsive element-binding protein-like 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000040624
InnateDB Gene IDBG-639423 (CREBL2)
Protein Structure
UniProt Annotation
Function Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle.
Subcellular Localization Nucleus {ECO:0000269PubMed:16352405}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0016032 viral process
GO:0030154 cell differentiation
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0045600 positive regulation of fat cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046326 positive regulation of glucose import
GO:0046889 positive regulation of lipid biosynthetic process
GO:0050821 protein stabilization
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR004827 Basic-leucine zipper domain
PFAM PF00170
PF07716
PRINTS
PIRSF
SMART SM00338
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0VD32
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 537195
UniGene Bt.10859
RefSeq NP_001069556
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC119861
GenPept AAI19862

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca