Version 5.4
Bos taurus Protein: SLC40A1
Summary
InnateDB Protein IDBP-691689.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC40A1
Protein Name solute carrier family 40 (iron-regulated transporter), member 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000045304
InnateDB Gene IDBG-639521 (SLC40A1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005381 iron ion transmembrane transporter activity
GO:0005515 protein binding
Biological Process
GO:0002260 lymphocyte homeostasis
GO:0003158 endothelium development
GO:0006826 iron ion transport
GO:0006879 cellular iron ion homeostasis
GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron
GO:0034755 iron ion transmembrane transport
GO:0043066 negative regulation of apoptotic process
GO:0048536 spleen development
GO:0060345 spleen trabecula formation
GO:0060586 multicellular organismal iron ion homeostasis
Cellular Component
GO:0005622 intracellular
GO:0005771 multivesicular body
GO:0005886 plasma membrane
GO:0008021 synaptic vesicle
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR009716 Ferroporti-1
IPR016196 Major facilitator superfamily domain, general substrate transporter
PFAM PF06963
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A0JNB7
UniProt Splice Variant
Entrez Gene 786541
UniGene Bt.71946
RefSeq NP_001071438
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC126601 DAAA02003913
GenPept AAI26602

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca