InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PSMD3

Summary

InnateDB Protein

IDBP-691690.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PSMD3

Protein Name

26S proteasome non-ATPase regulatory subunit 3

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000028608

InnateDB Gene

IDBG-639523 (PSMD3)

Protein Structure

UniProt Annotation

Function

Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 61 interaction(s) predicted by orthology.

Predicted by orthology
Total	61 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0030234	enzyme regulator activity

Biological Process

GO:0042176	regulation of protein catabolic process
GO:0050790	regulation of catalytic activity

Cellular Component

GO:0000502	proteasome complex
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005838	proteasome regulatory particle
GO:0016020	membrane
GO:0022624	proteasome accessory complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000717 Proteasome component (PCI) domain
IPR013143 PCI/PINT associated module
IPR013586 26S proteasome regulatory subunit, C-terminal

PFAM

PF01399
PF08375

PRINTS

PIRSF

SMART

SM00088
SM00753

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q2KJ46

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

504937

UniGene

Bt.51586

RefSeq

NP_001039365

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC105526

GenPept

AAI05527