Version 5.4
Bos taurus Protein: BT.24545
Summary
InnateDB Protein IDBP-691711.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.24545
Protein Name NKG2-D type II integral membrane protein
Synonyms KLRC; NKG2-D;
Species Bos taurus
Ensembl Protein ENSBTAP00000006469
InnateDB Gene IDBG-639540 (BT.24545)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019900 kinase binding
GO:0030246 carbohydrate binding
GO:0032394 MHC class Ib receptor activity
GO:0042288 MHC class I protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0030101 natural killer cell activation
GO:0032729 positive regulation of interferon-gamma production
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
GO:0050830 defense response to Gram-positive bacterium
GO:0071222 cellular response to lipopolysaccharide
Cellular Component
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
Protein Structure and Domains
PDB ID
InterPro IPR001304 C-type lectin
IPR002353 Type-2 ice-structuring protein
IPR008646 Herpesvirus UL45-like
IPR016187 C-type lectin fold
PFAM PF00059
PF05473
PRINTS PR00356
PIRSF
SMART SM00034
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MI53
UniProt Splice Variant
Entrez Gene 404058
UniGene Bt.24545
RefSeq NP_001068607
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02014354
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca