InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: QPCTL

Summary

InnateDB Protein

IDBP-691815.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

QPCTL

Protein Name

Glutaminyl-peptide cyclotransferase-like protein

Synonyms

gQC;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000032205

InnateDB Gene

IDBG-639635 (QPCTL)

Protein Structure

UniProt Annotation

Function

Responsible for the biosynthesis of pyroglutamyl peptides. {ECO:0000250}.

Subcellular Localization

Golgi apparatus membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008233	peptidase activity
GO:0008270	zinc ion binding
GO:0016603	glutaminyl-peptide cyclotransferase activity
GO:0016740	transferase activity
GO:0016746	transferase activity, transferring acyl groups
GO:0046872	metal ion binding

Biological Process

GO:0006508	proteolysis
GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase

Cellular Component

GO:0000139	Golgi membrane
GO:0005794	Golgi apparatus
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR007484 Peptidase M28

PFAM

PF04389

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q0V8G3

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

530871

UniGene

Bt.35335

RefSeq

NP_001069408

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC120182 BT025409 BT025454 BT026254 BT026255

GenPept

AAI20183 ABF57365 ABF57410 ABG67093 ABG67094