InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DMPK

Summary

InnateDB Protein

IDBP-691856.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DMPK

Protein Name

dystrophia myotonica-protein kinase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000017759

InnateDB Gene

IDBG-639646 (DMPK)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0017020	myosin phosphatase regulator activity

Biological Process

GO:0002028	regulation of sodium ion transport
GO:0006468	protein phosphorylation
GO:0006874	cellular calcium ion homeostasis
GO:0006998	nuclear envelope organization
GO:0008016	regulation of heart contraction
GO:0010657	muscle cell apoptotic process
GO:0010830	regulation of myotube differentiation
GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling
GO:0014853	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
GO:0016310	phosphorylation
GO:0050790	regulation of catalytic activity
GO:0051823	regulation of synapse structural plasticity

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0005886	plasma membrane
GO:0031307	integral component of mitochondrial outer membrane
GO:0031965	nuclear membrane
GO:0033017	sarcoplasmic reticulum membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR000961 AGC-kinase, C-terminal
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR014930 Myotonic dystrophy protein kinase, coiled coil
IPR017892 Protein kinase, C-terminal
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714
PF08826
PF00433

PRINTS

PR00109

PIRSF

SMART

SM00133
SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt