InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TAL1

Summary

InnateDB Protein

IDBP-691916.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TAL1

Protein Name

T-cell acute lymphocytic leukemia 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000006622

InnateDB Gene

IDBG-639733 (TAL1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 310 interaction(s) predicted by orthology.

Predicted by orthology
Total	310 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000976	transcription regulatory region sequence-specific DNA binding
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001085	RNA polymerase II transcription factor binding
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0042826	histone deacetylase binding
GO:0044212	transcription regulatory region DNA binding
GO:0046982	protein heterodimerization activity
GO:0046983	protein dimerization activity
GO:0070888	E-box binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001525	angiogenesis
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0007626	locomotory behavior
GO:0021527	spinal cord association neuron differentiation
GO:0030097	hemopoiesis
GO:0030099	myeloid cell differentiation
GO:0030182	neuron differentiation
GO:0030218	erythrocyte differentiation
GO:0030219	megakaryocyte differentiation
GO:0030220	platelet formation
GO:0030221	basophil differentiation
GO:0031334	positive regulation of protein complex assembly
GO:0035162	embryonic hemopoiesis
GO:0035855	megakaryocyte development
GO:0042127	regulation of cell proliferation
GO:0043249	erythrocyte maturation
GO:0045165	cell fate commitment
GO:0045637	regulation of myeloid cell differentiation
GO:0045648	positive regulation of erythrocyte differentiation
GO:0045799	positive regulation of chromatin assembly or disassembly
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045931	positive regulation of mitotic cell cycle
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048699	generation of neurons
GO:0051781	positive regulation of cell division
GO:0060018	astrocyte fate commitment
GO:0060216	definitive hemopoiesis
GO:0060217	hemangioblast cell differentiation
GO:0060218	hematopoietic stem cell differentiation
GO:0060375	regulation of mast cell differentiation
GO:2000036	regulation of stem cell maintenance

Cellular Component

GO:0000118	histone deacetylase complex
GO:0000790	nuclear chromatin
GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0033193	Lsd1/2 complex
GO:0043234	protein complex