InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GUSB

Summary

InnateDB Protein

IDBP-691932.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GUSB

Protein Name

beta-glucuronidase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000000941

InnateDB Gene

IDBG-639740 (GUSB)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004566	beta-glucuronidase activity
GO:0005102	receptor binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006027	glycosaminoglycan catabolic process
GO:0006898	receptor-mediated endocytosis
GO:0006907	pinocytosis
GO:0008333	endosome to lysosome transport

Cellular Component

GO:0005764	lysosome
GO:0009986	cell surface
GO:0016020	membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR006101 Glycoside hydrolase, family 2
IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich
IPR006103 Glycoside hydrolase, family 2, TIM barrel
IPR006104 Glycosyl hydrolases family 2, sugar binding domain
IPR008979 Galactose-binding domain-like
IPR017853 Glycoside hydrolase, superfamily

PFAM

PF00703
PF02836
PF02837

PRINTS

PR00132

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite