InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: RIMKLB

Summary

InnateDB Protein

IDBP-691938.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RIMKLB

Protein Name

Beta-citryl-glutamate synthase B

Synonyms

FAM80B; NAAGS;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000004262

InnateDB Gene

IDBG-639749 (RIMKLB)

Protein Structure

UniProt Annotation

Function

Catalyzes the synthesis of beta-citryl-L-glutamate and N-acetyl-L-aspartyl-L-glutamate. Beta-citryl-L-glutamate is synthesized more efficiently than N-acetyl-L-aspartyl-L-glutamate (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003824	catalytic activity
GO:0004363	glutathione synthase activity
GO:0005524	ATP binding
GO:0016874	ligase activity
GO:0046872	metal ion binding
GO:0072590	N-acetyl-L-aspartate-L-glutamate ligase activity
GO:0072591	citrate-L-glutamate ligase activity

Biological Process

GO:0006464	cellular protein modification process
GO:0006750	glutathione biosynthetic process

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR003806 ATP-grasp fold, DUF201-type
IPR004218 Prokaryotic glutathione synthetase, ATP-binding
IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX
IPR011761 ATP-grasp fold
IPR013651 ATP-grasp fold, RimK-type

PFAM

PF02655
PF02955
PF08443

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q0VCE9

PhosphoSite