InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ASS1

Summary

InnateDB Protein

IDBP-692111.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ASS1

Protein Name

Argininosuccinate synthase

Synonyms

ASS;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000027649

InnateDB Gene

IDBG-639901 (ASS1)

Protein Structure

UniProt Annotation

Function

Is indirectly involved in the control of blood pressure. {ECO:0000250}.

Subcellular Localization

Disease Associations

Note=Defects in ASS1 are the cause of a bovine form of citrullinemia.

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004055	argininosuccinate synthase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016597	amino acid binding
GO:0016874	ligase activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000050	urea cycle
GO:0000052	citrulline metabolic process
GO:0000053	argininosuccinate metabolic process
GO:0006526	arginine biosynthetic process
GO:0006531	aspartate metabolic process
GO:0008652	cellular amino acid biosynthetic process
GO:0045429	positive regulation of nitric oxide biosynthetic process
GO:0071499	cellular response to laminar fluid shear stress
GO:1903038	negative regulation of leukocyte cell-cell adhesion

Cellular Component

GO:0070062

extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001518 Argininosuccinate synthase
IPR018317 Queuosine biosynthesis protein QueC

PFAM

PF00764
PF06508

PRINTS

PIRSF

PIRSF006293

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P14568

PhosphoSite

PhosphoSite-

TrEMBL

W5VMT5

UniProt Splice Variant

Entrez Gene

280726

UniGene

Bt.1370

RefSeq

NP_776317

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC102474 JN082726 JN082727 KF933365 M26198

GenPept

AAA30388 AAI02475 AEH75987 AEH75988 AHH53526