InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ARHGAP35

Summary

InnateDB Protein

IDBP-692154.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ARHGAP35

Protein Name

Rho GTPase activating protein 35

Synonyms

GRLF1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020651

InnateDB Gene

IDBG-639946 (ARHGAP35)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005525	GTP binding

Biological Process

GO:0001843	neural tube closure
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0008360	regulation of cell shape
GO:0030900	forebrain development
GO:0043010	camera-type eye development
GO:0043116	negative regulation of vascular permeability
GO:0045892	negative regulation of transcription, DNA-templated

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0015629	actin cytoskeleton

Protein Structure and Domains

PDB ID

InterPro

IPR000198 Rho GTPase-activating protein domain
IPR001806 Small GTPase superfamily
IPR002713 FF domain
IPR008936 Rho GTPase activation protein
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00620
PF00071
PF01846

PRINTS

PR00449

PIRSF

SMART

SM00324
SM00441

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt