Version 5.4
| Bos taurus Protein: AKR1A1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-692283.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | AKR1A1 | ||||||||
| Protein Name | Alcohol dehydrogenase | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000000630 | ||||||||
| InnateDB Gene | IDBG-640072 (AKR1A1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | |||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR020471
Aldo/keto reductase subgroup IPR023210 NADP-dependent oxidoreductase domain |
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| PFAM |
PF00248
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| PRINTS |
PR00069
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| PIRSF |
PIRSF000097
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| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q3ZCJ2 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 618607 | ||||||||
| UniGene | |||||||||
| RefSeq | NP_001069981 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC102166 | ||||||||
| GenPept | AAI02167 | ||||||||