InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: UCK1

Summary

InnateDB Protein

IDBP-692296.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

UCK1

Protein Name

Uridine-cytidine kinase 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000014316

InnateDB Gene

IDBG-640085 (UCK1)

Protein Structure

UniProt Annotation

Function

Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004140	dephospho-CoA kinase activity
GO:0004849	uridine kinase activity
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016740	transferase activity

Biological Process

GO:0008152	metabolic process
GO:0015937	coenzyme A biosynthetic process
GO:0016310	phosphorylation
GO:0044206	UMP salvage
GO:0044211	CTP salvage

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000764 Uridine kinase like
IPR001977 Dephospho-CoA kinase
IPR006083 Phosphoribulokinase/uridine kinase
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF01121
PF00485

PRINTS

PR00988

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q0P5A4