Version 5.4
| Bos taurus Protein: TOE1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-692313.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | TOE1 | ||||||||
| Protein Name | Target of EGR1 protein 1 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000040666 | ||||||||
| InnateDB Gene | IDBG-640097 (TOE1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1 (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Nucleus, nucleolus {ECO:0000250}. Nucleus speckle {ECO:0000250}. Note=Localizes to nuclear speckles. {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR000571
Zinc finger, CCCH-type IPR006941 Ribonuclease CAF1 |
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| PFAM |
PF00642
PF04857 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00356
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q17QN2 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 513052 | ||||||||
| UniGene | Bt.28668 | ||||||||
| RefSeq | NP_001069062 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC118261 | ||||||||
| GenPept | AAI18262 | ||||||||