InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.64790

Summary

InnateDB Protein

IDBP-692435.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.64790

Protein Name

complement factor I

Synonyms

IF;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000045833

InnateDB Gene

IDBG-640204 (BT.64790)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity
GO:0005044	scavenger receptor activity
GO:0005515	protein binding
GO:0008233	peptidase activity
GO:0008236	serine-type peptidase activity
GO:0016787	hydrolase activity

Biological Process

GO:0006508	proteolysis
GO:0006898	receptor-mediated endocytosis
GO:0006952	defense response

Cellular Component

GO:0005615	extracellular space
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001190 SRCR domain
IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
IPR003614 Knottin, scorpion toxin-like
IPR003884 Factor I / membrane attack complex
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR017448 SRCR-like domain

PFAM

PF00530
PF00089
PF00057

PRINTS

PR00258
PR00722
PR00261

PIRSF

SMART

SM00020
SM00192
SM00505
SM00057
SM00202

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt