Version 5.4
Bos taurus Protein: ACHE
Summary
InnateDB Protein IDBP-692699.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACHE
Protein Name acetylcholinesterase precursor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000001517
InnateDB Gene IDBG-640435 (ACHE)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003990 acetylcholinesterase activity
GO:0004104 cholinesterase activity
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0016787 hydrolase activity
GO:0017171 serine hydrolase activity
GO:0042803 protein homodimerization activity
GO:0043236 laminin binding
GO:0043621 protein self-association
Biological Process
GO:0001919 regulation of receptor recycling
GO:0002076 osteoblast development
GO:0006581 acetylcholine catabolic process
GO:0008152 metabolic process
GO:0031623 receptor internalization
GO:0045212 neurotransmitter receptor biosynthetic process
GO:0051262 protein tetramerization
GO:0060041 retina development in camera-type eye
Cellular Component
GO:0005605 basal lamina
GO:0005615 extracellular space
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0031594 neuromuscular junction
GO:0045202 synapse
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000997 Cholinesterase
IPR002018 Carboxylesterase, type B
IPR013094 Alpha/beta hydrolase fold-3
PFAM PF00135
PF07859
PRINTS PR00878
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q7M382
UniProt Splice Variant
Entrez Gene 540446
UniGene Bt.1299
RefSeq XP_005225245
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02058274
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca