Version 5.4
Bos taurus Protein: PSME3
Summary
InnateDB Protein IDBP-692747.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PSME3
Protein Name proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000026535
InnateDB Gene IDBG-640458 (PSME3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 73 interaction(s) predicted by orthology.
Predicted by orthology
Total 73 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002039 p53 binding
GO:0005515 protein binding
GO:0061133 endopeptidase activator activity
GO:0097371 MDM2/MDM4 family protein binding
Biological Process
GO:0010950 positive regulation of endopeptidase activity
GO:0061136 regulation of proteasomal protein catabolic process
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0008537 proteasome activator complex
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR003185 Proteasome activator pa28, N-terminal domain
IPR003186 Proteasome activator pa28, C-terminal domain
IPR009077 Proteasome activator pa28
PFAM PF02251
PF02252
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BM26
UniProt Splice Variant
Entrez Gene 100336105
UniGene Bt.105322
RefSeq XP_002696046
HUGO HGNC:9570
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02049193
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca