Version 5.4
Bos taurus Protein: SIM2
Summary
InnateDB Protein IDBP-692784.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SIM2
Protein Name single-minded homolog 2 (Drosophila)
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000051685
InnateDB Gene IDBG-640518 (SIM2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006355 regulation of transcription, DNA-templated
GO:0007165 signal transduction
GO:0009880 embryonic pattern specification
GO:0030324 lung development
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000014 PAS domain
IPR001610 PAC motif
IPR010578 Single-minded, C-terminal
IPR013655 PAS fold-3
PFAM PF13188
PF13426
PF06621
PF08447
PRINTS
PIRSF
SMART SM00091
SM00086
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MKK8
UniProt Splice Variant
Entrez Gene 100337422
UniGene
RefSeq XP_003585341
HUGO HGNC:10883
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02003571 DAAA02003572
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca